Status:

COMPLETED

Use of Dehydroepiandrosterone (DHEA) in Women With Normal and Poor Ovarian Reserve Undergoing IVF

Lead Sponsor:

The University of Hong Kong

Conditions:

Female Infertility Due to Diminished Ovarian Reserve

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

The aim of the study is to evaluate the effect of DHEA supplement on ovarian reserve markers, ovarian response to gonadotrophins and cycle outcomes in patients with normal and poor ovarian reserve. S...

Detailed Description

Consecutive patients attending subfertility clinic at the Department of Obstetrics and Gynaecology, Queen Mary Hospital who are scheduled for in-vitro fertilization (IVF) treatment will be recruited a...

Eligibility Criteria

Inclusion

  • Indicated for IVF treatment according to our standard department protocol
  • Age \< 40
  • Regular menstrual cycles (21-35 days with \</= 4 days inter-cycle variation)
  • AFC not more than 15

Exclusion

  • Previous chemotherapy or pelvic irradiation
  • Polycystic ovarian syndrome or polycystic ovaries
  • On hormonal supplementation for any indication at the time of recruitment (e.g. estrogen, testosterone or DHEA)

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2013

Estimated Enrollment :

104 Patients enrolled

Trial Details

Trial ID

NCT01915186

Start Date

October 1 2010

End Date

September 1 2013

Last Update

December 20 2013

Active Locations (1)

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University of Hong Kong

Hong Kong, Hong Kong