Status:
COMPLETED
Kidney and Intestinal Markers for Early Detection of Organ Injury After Endovascular Aortic Repair
Lead Sponsor:
University Hospital Regensburg
Conditions:
Ischemia
Fatty Acid-Binding Proteins
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to investigate the predictive value of novel biomarkers and contrast-enhanced ultrasonography for early detection of abdominal end-organ (kidney and intestinum) hypoperfusion and ische...
Eligibility Criteria
Inclusion
- Existence of an aortic aneurysm with need of repair as indicated by the treating vascular surgeon
- Aortic stenting involving the origin of both mesenteric (i.e. superior and inferior mesenteric arteries) and kidney arteries
- Central line is present to perform repeated blood collections
- Written informed consent is obtained.
Exclusion
- Pre-existing severe liver or kidney injury (defined as spontaneous international normalized ratio (INR) \>2 or creatinine \>2 mg/dl or renal-replacement therapy in the pre-operative course.)
- Known allergy to ultrasound contrast media (exclusion for the CEUS but not for marker evaluation)
- Anemia with hemoglobin concentration \< 7g/dl
- Patients \< 18 years of age
- Patients not able to give written informed consent
Key Trial Info
Start Date :
July 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01915446
Start Date
July 1 2013
End Date
November 1 2014
Last Update
December 18 2014
Active Locations (1)
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1
University Medical Center Regensburg
Regensburg, Bavaria, Germany, 93053