Status:
AVAILABLE
18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia
Lead Sponsor:
Children's Hospital of Philadelphia
Conditions:
Congenital Hyperinsulinism (CHI)
Beckwith-Wiedemann Syndrome
Eligibility:
All Genders
Brief Summary
This purpose of this study is to determine the ability of an 18F-fluoro-L-dihydroxyphenylalanine (18F-DOPA) PET (Positron Emission Tomography) scan to detect a focal lesion of hyperinsulinism and dete...
Detailed Description
Patients with hyperinsulinemic hypoglycemia are at risk for neurological damage due to hypoglycemia. Early surgical intervention can be preventative. F-DOPA PET may be able to detect of a focal lesion...
Eligibility Criteria
Inclusion
- Subjects of any age with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and/or response to glucagon stimulation.
- Subjects who are eligible for pancreatic surgery regardless of prior pancreatic surgery
Exclusion
- Pregnant or lactating females
- Any other major illness or condition that in the investigator's judgment will substantially increase the risk associated with the subject's participation in this study
- Subjects who are not a candidate for pancreatic surgery
Key Trial Info
Start Date :
Trial Type :
EXPANDED_ACCESS
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01916148
Last Update
April 2 2025
Active Locations (1)
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1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104