Status:

COMPLETED

Acute Non-mechanical Lower Digestive Tract Disorders Should Distinguish Whether Colonic Lesions or Not in Critically Ill Patients

Lead Sponsor:

Nanjing PLA General Hospital

Conditions:

Critical Care Patient; Lower Digestive Tract Disorder;

Colon Lesions;

Eligibility:

All Genders

18-80 years

Brief Summary

The purpose of the study is to investigate acute non-mechanical lower digestive tract disorders should distinguish whether colonic lesions or not in critically ill patients

Detailed Description

The study was approved by the ethics committee of Jinling hospital and the medical school of nanjing university. This prospective study was performed at a surgical intensive care unit (SICU), which co...

Eligibility Criteria

Inclusion

  • Critical patients aging from 18 to 80 years old diagnosed with acute lower gastrointestinal dysfunction
  • enteral nutrition intolerance not due to upper gastriointestinal obstruction
  • Colonic distension: colonic diameter \>6 cm or ileocecus diameter \>9 cm under the view of computed tomography or abdomial X ray. Enteral nutrition intolerance was defined as enteral feeding \< 50% caculated needs or no feeding for three days -

Exclusion

  • mechanical intestinal obstruction (including tomor, stercoral obstruction etc); gastrointestinal hemorrhage within 72 hours; history of inflammatory bowel disease (ulcerative colitis or crohn's disease) or radiation enteritis; pregnancy; having the contradiction of proserine administration. -

Key Trial Info

Start Date :

January 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2012

Estimated Enrollment :

69 Patients enrolled

Trial Details

Trial ID

NCT01919060

Start Date

January 1 2007

End Date

January 1 2012

Last Update

August 8 2013

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