Status:
COMPLETED
The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
Lead Sponsor:
Yonsei University
Conditions:
Acute Kidney Injury
Eligibility:
All Genders
20-90 years
Phase:
PHASE4
Brief Summary
The purpose of study is to test whether perioperative sodium bicarbonate infusion can prevent acute kidney injury following open heart surgery in infective endocarditis patients.
Eligibility Criteria
Inclusion
- adult patients over the age of 20 scheduled for open heart surgery for infective endocarditis
Exclusion
- end stage renal disease (serum creatinine concentration \> 300 μmol/L)
- on dialysis
- chronic moderate to high dose corticosteroid therapy (\> 10 mg/day prednisolon or equivalent)
- preoperative severe hypernatremia (Na+ \> 150 mmol/L), alkalemia (PH \> 7.50), or pulmonary edema
- neurocognitive dysfunction
Key Trial Info
Start Date :
August 13 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 23 2016
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT01920126
Start Date
August 13 2013
End Date
August 23 2016
Last Update
July 17 2018
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, South Korea, 120-752