Status:

COMPLETED

Physiologic Plasticity of Intramyocardial Lipid Storage

Lead Sponsor:

Insel Gruppe AG, University Hospital Bern

Collaborating Sponsors:

Takeda

Conditions:

Lipid Metabolism

Eligibility:

MALE

18-30 years

Brief Summary

The main goal of the present study was to provide a technical basis for future studies assessing the role of cardiac lipids. More specifically, non-invasive MR-Spectroscopy (MRS) techniques will be us...

Detailed Description

Background Obesity is a well known risk factor for the development of glucose intolerance, type 2 diabetes mellitus and, consequently, diabetic complications like cardiovascular disease. Importantly,...

Eligibility Criteria

Inclusion

  • male
  • age 18-30
  • BMI \<25
  • healthy
  • written informed consent

Exclusion

  • contraindications to MRI examinations (claustrophobia, implanted devices (pacemaker, insulin pump, neurostimulators))

Key Trial Info

Start Date :

January 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2011

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT01921075

Start Date

January 1 2010

End Date

December 1 2011

Last Update

August 13 2013

Active Locations (1)

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1

Institute of Diagnostic Interventional and Pediatric Radiology, University Hospital Bern

Bern, Switzerland, CH-3010