Status:
COMPLETED
Periodontal Disease and Post-menopausal Osteoporosis
Lead Sponsor:
Universidad Nacional de Córdoba
Conditions:
Osteoporosis
Osteopenia
Eligibility:
FEMALE
45-70 years
Brief Summary
The aim of this study was to investigate the levels of RANKL and Osteoprotegerin, and their relationship in gingival crevicular fluid of post-menopausal women with osteoporosis/osteopenia and chronic ...
Detailed Description
81 active periodontal sites from 31 postmenopausal women aged 45-70 years with chronic periodontitis were studied. Samples of gingival crevicular fluid were collected by paper strips and ELISA test wa...
Eligibility Criteria
Inclusion
- Women between 45-70 years with Absorptiometry Dual Energy X-ray (DEXA).
- Control group: post-menopausal women with periodontal disease and normal osseous condition.
- Study group: post-menopausal womens with periodontal disease and osteoporosis/osteopenia with and without bisphosphonate treatment (risedronate or ibandronate 150 mg) for longer than 3 months before the study and another.
Exclusion
- Patients with history of aggressive periodontitis and had received any periodontal treatment when they entered the study
- Patients with any systemic illness (except osteopenia/osteoporosis)
- Patients who received antibiotic or non-steroidal anti-inflammatory therapy in the 6 months prior to the study.
Key Trial Info
Start Date :
May 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
81 Patients enrolled
Trial Details
Trial ID
NCT02184962
Start Date
May 1 2012
End Date
September 1 2013
Last Update
July 9 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Facultad de Odontología - Universidad Nacional de Córdoba
Córdoba, Córdoba Province, Argentina, 5000