Status:

COMPLETED

Open Label Study to Evaluate Long Term Efficacy, Safety and Tolerability of Repeated Dosing in Subjects With Crohn's Disease and Who Participated and Successfully Completed M14-115

Lead Sponsor:

AbbVie

Conditions:

Crohn's Disease

Eligibility:

All Genders

18-75 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the long term efficacy, safety, and tolerability of repeated administration of adalimumab in participants with Crohn's disease.

Eligibility Criteria

Inclusion

  • \- Subject successfully enrolled in and completed Study M14-115 (NCT02185014), including the Week 12 ileocolonoscopy.

Exclusion

  • If the Week 12 (Study M14-115; NCT02185014) colonoscopy shows evidence of dysplasia or malignancy.
  • Subject is not in compliance with prior and concomitant medication requirements throughout M14-115 (NCT02185014).
  • Subject who developed active Tuberculosis (TB) during M14-115 (NCT02185014), or subject who is non compliant with prophylaxis for latent tuberculosis (TB) initiated per M14-115 (NCT02185014) procedures.

Key Trial Info

Start Date :

August 12 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 3 2017

Estimated Enrollment :

252 Patients enrolled

Trial Details

Trial ID

NCT02185014

Start Date

August 12 2014

End Date

November 3 2017

Last Update

November 14 2018

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