Status:
COMPLETED
Vitamin-D Supplementation: Impact on Severe Pneumonia Among Under-five Children
Lead Sponsor:
International Centre for Diarrhoeal Disease Research, Bangladesh
Collaborating Sponsors:
Centers for Disease Control and Prevention
Conditions:
Pneumonia
Eligibility:
All Genders
3-59 years
Phase:
PHASE1
Brief Summary
Background: * Burden: Pneumonia is the leading cause of morbidity and mortality in under-five children, particularly in developing countries. * Knowledge gap: Although many studies have reported an a...
Detailed Description
Hypothesis to be tested: In a hypothesis testing research proposal, briefly mention the hypothesis to be tested and provide the scientific basis of the hypothesis, critically examining the observatio...
Eligibility Criteria
Inclusion
- Children of either sex aged 3 - 59 months, with a clinical diagnosis of severe pneumonia with or without diarrhea.
Exclusion
- Known case of hypercalcaemia or allergy to vitamin D, as determined by history or previous medical records.
- Congenital Heart disease, evidenced by clinical exam or past medical records.
- Renal or hepatic insufficiency, evidenced by clinical exams or past medical records.
- Known case of tuberculosis, evidenced by medical records
- Known case of asthma, evidenced by history and clinical exam findings.
- Critically ill children requiring ICU care, such as those with septic shock or cardiac arrest or apnoea.
- Received vitamin D or calcium supplementation within the last 4 weeks before current admission, as evidenced by history or medical prescription.
- Any children diagnosed as hypernatraemia during the main phase of the study.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2017
Estimated Enrollment :
197 Patients enrolled
Trial Details
Trial ID
NCT02185196
Start Date
June 1 2014
End Date
December 31 2017
Last Update
August 6 2019
Active Locations (1)
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1
Dhaka Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh
Dhaka, Bangladesh, 1212