Status:
UNKNOWN
Evaluation of T1rho Magnetic Resonance Imaging for Diagnosis of Cartilage Lesions in Hips With Developmental Dysplasia
Lead Sponsor:
Ottawa Hospital Research Institute
Collaborating Sponsors:
Zimmer Biomet
The Ottawa Hospital Academic Medical Association
Conditions:
Developmental Dysplasia of the Hip
Eligibility:
All Genders
18-100 years
Brief Summary
One of the leading causes of hip arthritis is developmental dysplasia of the hip (DDH). DDH can lead to major damage in the hip joint and may result in hip arthritis later in life. Patients recruited ...
Detailed Description
The start of arthritis can first be detected in certain molecules in the joint. Proteoglycan is a molecule that is important to cartilage structure, and is lost as arthritis develops. Magnetic resonan...
Eligibility Criteria
Inclusion
- patients with a diagnosis of developmental dysplasia of the hip (DDH)
Exclusion
- patients under the age of 18
- pregnancy and/or lactation
- non-MRI compatible implants (stents, electronic devices, cardiac pacers or wires)
- severe claustrophobia
- prior contrast allergic reaction
- kidney impairment
- previous hip surgery
- osteoarthritis on conventional radiographs (Tönnis Grade\>0)
- additional underlying hip diseases such as posttraumatic arthritis, Legg-Calvé-Perthes-Disease (LCPD), or slipped capital femoral epiphysis (SCFE)
Key Trial Info
Start Date :
July 25 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2021
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT02185365
Start Date
July 25 2017
End Date
December 1 2021
Last Update
June 23 2021
Active Locations (1)
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1
Ottawa Hospital - General Campus
Ottawa, Ontario, Canada, K1H8L6