Status:

COMPLETED

Proof Of Concept : Immunogenicity and Safety of hepB Injection in the Dermis Using VAX-ID

Lead Sponsor:

Novosanis NV

Conditions:

Hepatitis B

Eligibility:

All Genders

18-35 years

Phase:

PHASE1

Brief Summary

A proof of concept (POC) study will be conducted in 44 volunteers that have been fully vaccinated against hepatitis B in the past (at least 5 years ago) to assess the safety and immunogenicity of intr...

Eligibility Criteria

Inclusion

  • healthy adults, checked anamnestically (based on medical history) at entry of the study
  • 18-35 years
  • vaccination status: fully vaccinated against hepatitis B at least 5 years ago, with proof of vaccine response (to avoid non-response among the subjects). Subjects has to ask for a document of this proof at the service occupational medicine of the University of Antwerp.
  • capable of understanding, reading and writing Dutch

Exclusion

  • other vaccination(s) 4 weeks before study onset
  • pregnancy and lactation (women will be questioned during anamnesis)
  • plan to have other vaccination during the study period

Key Trial Info

Start Date :

March 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT02186977

Start Date

March 1 2016

End Date

December 1 2016

Last Update

March 28 2017

Active Locations (1)

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Centre for the Evaluation of Vaccination Vaccine & Infectious Disease Institute

Wilrijk, Antwerp, Belgium, 2610