Status:
WITHDRAWN
Determining in Vitro Properties of Epithelial Cells From Individuals With Genetic Variants Associated With Idiopathic Pulmonary Fibrosis
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Idiopathic Pulmonary Fibrosis
Healthy
Eligibility:
All Genders
18-85 years
Brief Summary
The investigators are trying to understand the role of specific genes in the function of airway surface cells. The investigators know that there are some common genetic markers that are associated wit...
Eligibility Criteria
Inclusion
- Age greater than 18 years of age
- Ability to provide informed consent
- Patent bilateral nares
Exclusion
- Significant nasal or sinus disease precluding nasal brushing
- A history of or ongoing epistaxis (nose-bleeding)
- Acute upper respiratory illness
- Ongoing treatment of respiratory or sinus illness with antibiotics
- Pregnancy
- Age less than 18 years
- Infection with human immunodeficiency virus (HIV) or viral hepatitides (Hepatitis B, Hepatitis C)
- Prior volunteer for the same study
- Known diagnosis of cystic fibrosis or other ciliary disorder (example: primary ciliar dyskinesia)
- Treatment with anticoagulants (examples: warfarin/coumadin, low molecular weight heparins, direct thrombin inhibitors such as dabigatran, anti-platelet agents such as P2Y12 inhibitors like clopidogrel and prasugrel, aspirin, ticagrelor, or factor Xa inhibitors such as rivaroxaban)
- Known thrombocytopenia (example: immune thrombocytopenic purpura)
- Ongoing chemotherapy
- Known platelet dysfunction or bleeding diathesis/hemophilia
Key Trial Info
Start Date :
July 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2015
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02187393
Start Date
July 1 2015
End Date
November 1 2015
Last Update
November 30 2015
Active Locations (1)
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1
University of Colorado Denver
Aurora, Colorado, United States, 80045