Status:

COMPLETED

Refinement and Clinical Evaluation of the H-Man for Arm Rehabilitation After Stroke

Lead Sponsor:

Tan Tock Seng Hospital

Collaborating Sponsors:

National Medical Research Council (NMRC), Singapore

Conditions:

Stroke

Eligibility:

All Genders

21-85 years

Phase:

NA

Brief Summary

Locally, stroke remains the 4th cause of death, causing 8.4% of deaths annually in Singapore, and a leading cause of neurological disability worldwide. Nearly 40% of the stroke survivors will require ...

Detailed Description

As above

Eligibility Criteria

Inclusion

  • First ever clinical stroke (ischaemic or haemorrhagic) confirmed on brain imaging
  • Duration post stroke: 3 months to 24 months
  • Age 21 to 85 years
  • Hemiplegic pattern of arm motor impairment with Shoulder abduction MRC motor power \>/= 3/5 and elbow flexion MRC motor power \>/= 3/5
  • Affected upper limb Fugl Myer Motor Assessment (FMMA) scale 20-50
  • And / or associated motor incoordination or motor ataxia

Exclusion

  • Non stroke related causes of arm motor impairment
  • Medical conditions incompatible with research participation: uncontrolled medical illnesses (hypertension or diabetes, heart failure, asthma, depression, end stage renal failure, terminal malignancy), life expectancy \<6 months, unhealed fractures or severe arm pain (visual analogue scale VAS \> 5/10, pregnancy
  • Inability to tolerate sitting for 90 minutes.
  • Local factors which preclude robotic interfacing or may be worsened by intensive arm therapy: spasticity of Modified Ashworth Scale grades 3-4, skin wounds, shoulder pain VAS \>5/10, active fractures or arthritis or fixed flexion contractures of shoulder, elbow, wrist or fingers incompatible with interface with the H-man robot.
  • Severe sensory impairment of affected limb
  • Severe visual impairment, hemispatial neglect or homonymous hemianopia
  • Cognitive impairments or uncontrolled behaviour. (Folstein mini mental state exam MMSE \<26/28)

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2018

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT02188628

Start Date

July 1 2014

End Date

March 31 2018

Last Update

September 12 2019

Active Locations (1)

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Tan Tock Seng Rehabilitation Centre

Singapore, Singapore, 569766