Status:
COMPLETED
Effects of Creatine Supplementation on Muscle Mass and Function Among Older Women Subjected to Resistance Training
Lead Sponsor:
University of Chile
Conditions:
Muscle Weakness
Eligibility:
FEMALE
60-80 years
Phase:
PHASE3
Brief Summary
To determine, in a double blind trial, the effects of creatine supplementation during 12 weeks on muscle mass and function of community living older women subjected to resistance training. Material an...
Detailed Description
Healthy women of middle and low socioeconomic level, living in the community and aged between 60 and 75 years, will be invited to participate in this study. At baseline and after signing an informed ...
Eligibility Criteria
Inclusion
- Absence of a significant disability, defined as the capacity to reach the health center by their own means with the use of any aid such as canes or wheelchairs
- Absence of disabling diseases such as cardiac, respiratory, liver or kidney failure or active cancer
- Absence of decompensated diabetes mellitus of hypertension. Diabetic patients with repeated fasting blood glucose levels below 120 mg/dl and a glycosylated hemoglobin below 7% will be allowed to participate. Hypertensive patients in treatment with a blood pressure (measured in at least two occasions) below 140/90 mm Hg will also be allowed.
Exclusion
- Smoking or excessive consumption of alcohol
- Use of medications that can cause muscle dysfunction or limit exercise capacity such as adrenal steroids, chemotherapeutic agents, statins in high doses (ie more than 40 mg/day of atorvastatin) or muscle relaxants.
- Having a severe osteoarticular disease such as rheumatoid arthritis or severe osteoarthritis, with precludes participating in an exercise training program.
- Recent use of ergogenic supplements such as creatine.
- Being engaged in an active exercise training program.
- Being illiterate or having a level of cognitive dysfunction that precludes the free signature of a written informed consent to participate in the study.
- Any personal or socioeconomic condition that, in opinion of the research team, will hamper the correct compliance of the participant with the research program.
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT02188849
Start Date
October 1 2014
End Date
August 1 2015
Last Update
October 30 2015
Active Locations (1)
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1
INTA University of Chile
Santiago, Metropolitan, Chile, 7830489