Status:
COMPLETED
Brain Imaging Studies of the Effect of Inhalant Use Disorder
Lead Sponsor:
Miguel Ángel Mendoza Meléndez
Collaborating Sponsors:
National Institute of Neurology and Neurosurgery, Mexico
Conditions:
Inhalant Use Disorder
Eligibility:
MALE
18-40 years
Brief Summary
Inhalants substance misuse is an important public health problem whose prevalence is approximately 1% in the general population and 7% among high school students in Mexico. Furthermore Inhalants subst...
Eligibility Criteria
Inclusion
- Males between 18 to 40 years old.
- Subjects must have a diagnosis of inhalant use disorder who are under a treatment program for addictive disorders or normal control without a history of drug abuse or dependency. Control participants must be matches with the inhalant use disorder participants according to age and years of education.
- Subjects in both the inhalant use disorder and control groups will be volunteers who signed informed consent.
Exclusion
- Epilepsy or clinically relevant seizures in the last year
- Cognitive impairment evaluated through Mini-Mental State Examination
- Psychosis
- Manic or hypomanic episode
- Moderate or severe suicide risk
- Panic disorder
- Claustrophobia: Subjects will be questioned about their potential discomfort in being in an enclosed space, such as a PET or MRI scanner.
- History of head trauma with loss of consciousness \> 30 min.
- Neurological surgical procedures
- Diabetes
- Positive test for hippuric acid
- Current use of antipsychotic medication
- Current illnesses, painful conditions or other disorders, which in the judgment of the investigators, might invalidate the scientific goals of the study or pose undesirable difficulties or risks for subjects
- In the case for magnetic resonance imaging, Individuals who would be unable to undergo a MRI scan, for example, individuals who have metal clips in their body, metallic prostheses (i.e., replacement body parts, such as a hip joint), a pacemaker, or other pieces of metal in their body (shrapnel, metal filings, etc.).
Key Trial Info
Start Date :
November 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 30 2016
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT02188914
Start Date
November 1 2014
End Date
July 30 2016
Last Update
August 17 2017
Active Locations (1)
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1
National Institute of Neurology and Neurosurgery Manuel Velasco Suarez
Mexico City, Mexico, 14269