Status:

COMPLETED

Evaluation of the Safety and Efficacy of an Oxalate Gel or Negative Control on Dentinal Hypersensitivity

Lead Sponsor:

Procter and Gamble

Conditions:

Dentin Sensitivity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will compare the safety and effectiveness of a potassium oxalate desensitizer or negative control on dentinal hypersensitivity.

Eligibility Criteria

Inclusion

  • be at least 18 years of age;
  • provide written informed consent prior to participation and be given a signed copy of the informed consent form;
  • complete a confidentiality disclosure agreement;
  • be in good general health as determined by the Investigator/designee;
  • agree not to participate in any other oral/dental product studies during the course of this study;
  • agree to delay any dentistry (including dental prophylaxis) until the study has been completed;
  • agree to refrain from the use of any non-study oral hygiene products;
  • agree to return for all scheduled visits and follow study procedures; and.
  • have at least one tooth with a Schiff sensitivity score of at least 1 in response to air challenge and a Yeaple Probe score of 10-40 in response to tactile challenge

Exclusion

  • self-reported pregnancy or nursing;
  • severe periodontal disease, as characterized by purulent exudate, generalized mobility, and/or severe recession;
  • active treatment of periodontitis;
  • fixed facial orthodontic appliances;
  • a history of kidney stones;
  • known allergies to the following ingredients; aqua, glycerin, cellulose gum, dipotassium oxalate, carbomer, sodium hydroxide, sodium benzoate, and potassium sorbate
  • any diseases or conditions that might interfere with the safe completion of the study; or
  • an inability to undergo any study procedures.

Key Trial Info

Start Date :

June 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2014

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT02189382

Start Date

June 1 2014

End Date

July 1 2014

Last Update

August 20 2018

Active Locations (1)

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Silverstone Research Group

Las Vegas, Nevada, United States, 89146