Status:
COMPLETED
Efficacy and Safety Study of Calcipotriol Betamethasone Plus Calcipotriol in Sequential Therapy to Psoriasis
Lead Sponsor:
Xijing Hospital
Conditions:
Psoriasis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Evaluate the efficacy and safety of Calcipotriol Betamethasone Ointment and Calcipotriol Ointment in sequential therapy
Detailed Description
1.240 subjects will be randomized 1:1:1 divided into the 3 groups 2.Week0 to Week4,each group were treated with Calcipotriol Betamethasone Ointment 3.Week4 to Week12, the there group were respectively...
Eligibility Criteria
Inclusion
- Subjects who signed Informed Consent Form；
- Male or female subjects 18-65 years of age；
- Clinically confirmed diagnosis of plaque psoriasis as per the diagnostic criteria for psoriasis vulgaris specified in Clinical Dermatology.
- Involved area 1-10% of the body surface area.
Exclusion
- Incompliance with the diagnosis of plaque psoriasis or plaque area \> 10% of the body surface area.
- Erythrodermic psoriasis, psoriasis arfhropathica or pustular psoriasis;
- Known allergy to any component of the test or control drug；
- Concomitant allergic skin disease such as eczema， contact dermatitis and urticaria, or other serious and/or extensive skin disease；
- Systemic medication or ultraviolet therapy for psoriasis within 4 weeks prior to study initiation；
- Topical use of external drug for psoriasis within 2 weeks prior to study initiation；
- Women of child-bearing potential who are pregnant, plan to become pregnant during study or are lactating；
- Glucocorticoid or immunodepressant, or hypoleukemia due to tumor or chemotherapy within the last 4 weeks；
- Serious life-threatening condition that allows a life expectancy of less than 2 months；
- Inability to guarantee taking medications and completing visits as scheduled during the study;
- Serious infection that is not suitable for external treatment；
- Any other condition that the investigator deems unsuitable for entering the study.
Key Trial Info
Start Date :
November 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
230 Patients enrolled
Trial Details
Trial ID
NCT02191007
Start Date
November 1 2013
End Date
May 1 2014
Last Update
July 15 2014
Active Locations (1)
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1
Xijing Hospital
Xi'an, Shaanxi, China, 710000