Status:
COMPLETED
A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia
Lead Sponsor:
Beijing HuiLongGuan Hospital
Conditions:
Schizophrenia
Eligibility:
All Genders
25-60 years
Phase:
NA
Brief Summary
The purpose of this study is to compare the efficacy and side effects of 6 commonly used antipsychotic drugs in the treatment of schizophrenia in a Chinese population.
Detailed Description
The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents has been incompletely addressed, though newer agents are currently used far more co...
Eligibility Criteria
Inclusion
- Patients' diagnoses is based on the results of the Structured Clinical Interview for DSM (SCID) using the criteria of the fourth edition of the Diagnostic and Statistical Manual (DSM-IV), physical exams and routine chemistry, and hematology laboratory tests. Attending-level psychiatrists will use a Chinese translation of the SCID to interview patients and their family members, who are given freedom to ask additional questions if respondents do not understand the standard probes.
- Patients must meet the following criteria: (1) diagnosis of schizophrenia; (2) duration of illness more than 2 years; (3) between 25 and 60 years of age; and (5) have NOT received antipsychotic medication for at least 1 month;(6) acute exacerbations of chronic inpatients.
- A complete medical history, electroencephalograms and electrocardiogram are obtained, and a physical examination and laboratory tests are performed at study entrance. None of the study participants have abnormal findings on these tests.
Exclusion
- \-
Key Trial Info
Start Date :
June 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
550 Patients enrolled
Trial Details
Trial ID
NCT02192723
Start Date
June 1 2012
End Date
June 1 2014
Last Update
July 12 2016
Active Locations (1)
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1
Beijing HuiLongGuan Hospital
Beijing, China, 100096