Status:
COMPLETED
Microparticles in Severe Aortic Stenosis
Lead Sponsor:
InCor Heart Institute
Conditions:
Aortic Valve Stenosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Microparticles are small cell fragments that can induce fat plaques, calcification and formation of thrombus. They can be released through multiple stimulations, but also the high flow of blood throug...
Detailed Description
Microparticle (MPs) levels and subtypes according to endothelial cell, macrophage and platelet markers will be measured by flow-cytometry using appropriate fluorochromes. Patient baseline (including m...
Eligibility Criteria
Inclusion
- Clinical indication to be treated with transcatheter aortic valve replacement.
Exclusion
- Non native aortic valve
- Moderate aortic regurgitation
- The following complications following valve implantation: patient instability, need for vasoactive pressors, sepsis and severe infections, stroke.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2015
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT02193035
Start Date
June 1 2014
End Date
June 1 2015
Last Update
April 13 2016
Active Locations (1)
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1
Heart Institute - InCor. University of Sao Paulo Medical School
São Paulo, São Paulo, Brazil, 05403-000