Status:
COMPLETED
Physiologic Effect of Spices Ingestion
Lead Sponsor:
Société des Produits Nestlé (SPN)
Conditions:
Healthy
Eligibility:
MALE
20-50 years
Phase:
NA
Brief Summary
Human studies have shown that capsaicin, a compound extracted from chilly peppers, can stimulate certain physiologic functions (for example, energy expenditure, thermogenesis, lipid oxidation, heart r...
Detailed Description
Primary objective and outcome: The main objective of this study is to establish a methodology to evaluate the acute impact of spice ingestion on metabolism and autonomic nervous system activity. Pri...
Eligibility Criteria
Inclusion
- Healthy
- BMI: 19-25 kg/m2, ≥ 60 kg body weight
- Moderate spicy food eaters
- Having signed the informed consent.
Exclusion
- Any gastrointestinal disorder
- Subject sensitive or not used to eat spicy food
- Smokers
- Subject with beard or mustache
- Abnormal thyroid function
- Intake of medication that could affect body weight and/or energy expenditure
- Weight loss \> 5% in the last 3 months
- Under antibiotics or regular treatments (medical or nutritional program) affecting body weight, appetite, energy expenditure, lipid-lowering, hypertension or inflammation or glucose control for the last 3 months or taking hormone replacement therapy
- History of allergy
- Physical activity level \> 300 min of moderate or intense exercise per week
- Have a alcohol consumption higher than than 1 drink/day
- Consumption of illicit drugs
- Subject who cannot be expected to comply with the study procedures, including consuming the test products
- Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study
Key Trial Info
Start Date :
May 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT02193438
Start Date
May 1 2011
End Date
August 1 2012
Last Update
July 17 2014
Active Locations (1)
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1
NESTEC / Metabolic Unit
Lausanne, Switzerland, 1026