Status:

UNKNOWN

Preoperative Concurrent Chemoradiotherapy for Locally Advanced Gastroesophageal Junction or Upper Gastric Adenocarcinoma

Lead Sponsor:

Peking University

Collaborating Sponsors:

Chinese PLA General Hospital

Peking University People's Hospital

Conditions:

Gastroesophageal Junction Adenocarcinoma

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

PHASE3

Brief Summary

Preoperative chemoradiotherapy(CRT) had been introduced in the comprehensive treatment of gastroesophageal junction and upper gastric cancers in the decade.According to some researches,CRT had shown i...

Eligibility Criteria

Inclusion

  • Histologically proven adenocarcinoma of the gastroesophageal junction.
  • Clinical stage diagnosed by endoscopic ultrasound(EUS) or computed tomography(CT) as T3-4NxM0 tumors,according to American Joint Committee on Cancer (AJCC) 7th edition.
  • Eastern Cooperative Oncology Group (ECOG) performance status≤2.
  • Informed consent obtained.

Exclusion

  • Combined with other malignant tumors.
  • Eastern Cooperative Oncology Group (ECOG) performance status\>2.
  • Combined with severe organ dysfunction.
  • Pregnancy

Key Trial Info

Start Date :

January 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2020

Estimated Enrollment :

214 Patients enrolled

Trial Details

Trial ID

NCT02193594

Start Date

January 1 2014

End Date

May 1 2020

Last Update

June 8 2015

Active Locations (1)

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Beijing Cancer Hospital

Haidian District, Beijing Municipality, China, 100142