Status:
COMPLETED
Comparison of Nasal Steroids After FESS in CRSwNP
Lead Sponsor:
Yale University
Conditions:
Sinusitis
Nasal Polyps
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to compare intranasal fluticasone spray with budesonide nasal saline rinses in both the upright and head forward positions in patients who have had functional endoscopic s...
Detailed Description
Chronic rhinosinusitis (CRS) is an inflammatory condition of the lining of the nose and sinuses that lasts 12 weeks or longer with objective evidence of mucosal inflammation (1). CRSwNP is characteriz...
Eligibility Criteria
Inclusion
- Adult patients who have had FESS for CRSwNP within the study period
Exclusion
- Patients who are under the age of 18
- Concurrent oral corticosteroid use of the equivalent of greater than 10 mg of prednisone use per day
- The use of medications that accelerate the clearance of systemic cortisol (Dilantin, rifampin, amphetamines, and lithium)
- The use of medications that inhibit the clearance of systemic cortisol (ketoconazole, amphotericin B, bupropion, fluoroquinolones)
- Known hypersensitivity to corticosteroids
- A personal history of Wegener's Granulomatosis or other autoimmune disease with nasal manifestations
Key Trial Info
Start Date :
January 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT02194062
Start Date
January 1 2015
End Date
August 1 2015
Last Update
February 8 2018
Active Locations (2)
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1
Yale Physicians Bldg
New Haven, Connecticut, United States, 06510
2
Yale ENT Stratford
Stratford, Connecticut, United States, 06614