Status:
COMPLETED
Combined Medication for Improved Analgesia in Superficial Pain
Lead Sponsor:
Brigham and Women's Hospital
Collaborating Sponsors:
Beth Israel Deaconess Medical Center
Conditions:
Pain
Eligibility:
All Genders
18-40 years
Phase:
PHASE3
Brief Summary
This research study is being done to assess if a combination of medications can enhance the relief of superficial pain (pain at the surface of the skin, such as sunburn pain). The investigators also w...
Eligibility Criteria
Inclusion
- Male and female healthy volunteers.
- 18-40 years of age.
- Ability to read and understand English; English can be a second language provided that the participant feels that he/she understand all the questions used in the assessment measures.
Exclusion
- Chronic pain condition or chronic or current treatment with any pain medication.
- Presence of any illness or medication use that is judged to interfere with the trial. For example: psychiatric disorder, medication that can influence cognition or emotional processing, i.e. sleep medication, antidepressants, anti-convulsants or opioids.
- Unwillingness to receive brief pain stimulation administered by a heat probe on the hand.
- Allergy or contra-indication to receiving nonsteroidal anti-inflammatory medication and atropine (Treatment with antidepressants, neuroleptics, antihistaminic, levodopa, anti-acids. Pregnancy, breast-feeding, myasthenia gravis, pyloric stenosis, gastro-esophageal reflux, gastric ulcer, constipation, prostatic enlargement, glaucoma, cardio-pulmonary condition -including tachycardia, arrhythmia, arteriosclerosis-, hyperthyroidism, high blood pressure, genetic disease, kidney failure)
Key Trial Info
Start Date :
April 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2017
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02194088
Start Date
April 1 2014
End Date
June 1 2017
Last Update
July 3 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Brigham And Women's Hospital
Boston, Massachusetts, United States, 02115