Status:
WITHDRAWN
Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors
Lead Sponsor:
Sue O'Dorisio
Collaborating Sponsors:
National Cancer Institute (NCI)
Ride for Kids
Conditions:
Acoustic Schwannoma
Adult Anaplastic Astrocytoma
Eligibility:
All Genders
6-29 years
Phase:
NA
Brief Summary
This pilot clinical trial studies gallium Ga 68-edotreotide (68Ga-DOTATOC) positron emission tomography (PET)/computed tomography (CT) in finding brain tumors in younger patients. Diagnostic procedure...
Detailed Description
PRIMARY OBJECTIVES: I. To determine if 68Ga-DOTATOC (gallium Ga 68-edotreotide) PET when combined with magnetic resonance imaging (MRI) will differentiate embryonal tumors such as medulloblastoma and...
Eligibility Criteria
Inclusion
- Patients presenting with brain tumors will be eligible for this study
- Eligible subjects must be able and willing to undergo the procedures of the study
- Electronic version of pre-surgery MRI must be available for co-registration purposes
- Fresh frozen tumor, and/or paraffin block of biopsy or resected tumor is recommended, but not required to determine expression of somatostatin receptors in tumor by immunohistochemistry and/or quantitative polymerase chain reaction (qPCR)
Exclusion
- Women who are pregnant or breastfeeding
- Presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin of body that would preclude obtaining an MRI as part of the initial study evaluation
- Inability to complete the needed investigational and standard-of-care imaging examinations due to other reasons
- Presence of any additional medical condition such as inter-current illness, or other extenuating circumstance that, in the opinion of the investigator, may significantly interfere with study compliance
Key Trial Info
Start Date :
September 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2017
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT02194452
Start Date
September 1 2013
End Date
March 1 2017
Last Update
April 28 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242