Status:

COMPLETED

Magnesium Balance of Citrate-based Continuous Venovenous Hemofiltration, Effect of Citrate Dose.

Lead Sponsor:

Ziekenhuis Oost-Limburg

Conditions:

Critically Ill

Acute Kidney Injury

Eligibility:

All Genders

Phase:

NA

Brief Summary

Rationale: A higher citrate dose during continuous venovenous hemofiltration provides better anticoagulation but possibly a higher risk of citrate accumulation in case of metabolic limitations. A hig...

Eligibility Criteria

Inclusion

  • Critically ill patients requiring CRRT for AKI (RIFLE criteria)
  • Written informed consent from the patient or legal representative

Exclusion

  • pre-existing chronic renal insufficiency requiring dialysis
  • chronic immunosuppression
  • liver cirrhosis Child-Pugh C
  • severe or shock-related hepatitis
  • Pregnancy

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2017

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT02194569

Start Date

July 1 2014

End Date

June 1 2017

Last Update

April 2 2018

Active Locations (1)

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1

Ziekenhuis Oost Limburg

Genk, Limburg, Belgium, 3600