Status:

COMPLETED

Effect of Laparoscopic Operation on Rocuronium and Cisatracurium: Pharmacokinetic and Pharmacodynamic Analysis

Lead Sponsor:

Fudan University

Conditions:

C.Delivery; Surgery (Previous), Gynecological

Eligibility:

FEMALE

18-60 years

Phase:

PHASE4

Brief Summary

The investigators investigated whether laparoscopic versus open surgical approaches affected the pharmacokinetic and pharmacodynamic of a single bolus dose of rocuronium or cisatracurium.

Eligibility Criteria

Inclusion

  • American Society of Anesthesiology 1-2
  • BMI 18-30 kg.m-2
  • elective gynaecological operations under general anaesthesia

Exclusion

  • cirrhosis
  • hepatitis
  • hepatoma
  • heart failure
  • arrhythmia
  • renal dysfunction
  • electrolyte disturbances
  • acid-base imbalances
  • neuromuscular disorders

Key Trial Info

Start Date :

January 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT02194855

Start Date

January 1 2015

End Date

June 1 2016

Last Update

August 12 2020

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