Status:
UNKNOWN
Trial of Using SIB-IMRT in Preoperative Radiotherapy for Locally Advanced Rectum Cancer
Lead Sponsor:
Chinese Academy of Medical Sciences
Conditions:
Rectal Cancer
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
Pathological complete response, (pCR) correlates with a favorable overall prognosis in locally advanced rectal cancer patients underwent preoperative chemoradiation, so obtaining a pCR might be benefi...
Eligibility Criteria
Inclusion
- histopathologically confirmed rectal adenocarcinoma with an inferior border within 15 cm of the anal verge
- the tumor has to have evidence of T3 or T4 disease on Magnetic Resonance Imaging (MRI) or endoluminal ultrasound
Exclusion
- metastatic disease
- Eastern Cooperative Oncology Group (ECOG) performance status \> 3
- patients not deemed fit for radiotherapy, capecitabine or surgery
- pregnant or lactating patients
- women with child bearing potential who lack effective contraception
- patients below 18 years old
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2015
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT02195141
Start Date
January 1 2014
End Date
December 1 2015
Last Update
February 4 2015
Active Locations (1)
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1
Cancer Hospital, CAMS
Beijing, China, 100021