Status:

COMPLETED

Clinical Evaluation of Cohera Sylys Surgical Sealant as an Adjunct to Standard Bowel Anastomosis Closure

Lead Sponsor:

Cohera Medical, Inc.

Conditions:

Stoma Reversal Procedure

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

A first in human study evaluating the safety of Sylys Surgical Sealant in protecting the anastomotic junction created during a stoma reversal procedure.

Eligibility Criteria

Inclusion

  • Be at least 18 years of age
  • Be in good general health in the opinion of the investigator with no conditions that would significantly impact wound healing as determined by medical history and review of recent concomitant medications
  • Be scheduled for an ileostomy reversal procedure
  • Be willing to follow instructions for incision care
  • Agree to return for all follow-up evaluations specified in this protocol
  • Sign informed consent

Exclusion

  • Anesthesia risk judged to be higher than ASA2
  • Have severe co-morbid conditions that pose a high risk for surgery and adequate recovery (e.g., heart disease)
  • Any condition involving compromised immune system
  • Any condition known to effect wound healing, such as collagen vascular disease
  • Known blood clotting disorder
  • Be receiving antibiotic therapy for pre-existing condition or infection
  • Concurrent use of fibrin sealants or other anastomosis care devices
  • Be currently taking systemic steroids or immunosuppressive agents
  • Have known or suspected allergy or sensitivity to any test materials or reagents
  • Be participating in any current clinical trial or have participated in any clinical trial within 30 days of enrollment in this study

Key Trial Info

Start Date :

April 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2013

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT02196519

Start Date

April 1 2013

End Date

September 1 2013

Last Update

July 22 2014

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