Status:
COMPLETED
Hypoxia and Exercise in the Elderly
Lead Sponsor:
Hannover Medical School
Collaborating Sponsors:
German Diabetes Center
Conditions:
Elderly Persons
Eligibility:
All Genders
55-75 years
Phase:
NA
Brief Summary
Ageing is the primary risk factor for most chronic diseases including type 2 diabetes mellitus. Sarcopenia and muscular mitochondrial dysfunction with aging are crucial mechanisms leading to decreased...
Eligibility Criteria
Inclusion
- 55 to 75 years of age
- body mass index: 20 - 35 kg/m2
- weight stable during last 6 months before screening (weight change \< 2% body weight)
- HOMA-index of insulin resistance ≥ 2 to 4 units
Exclusion
- more than 1 hour of scheduled exercise training per week
- known diagnosis of type 2 diabetes or measured HbA1c \> 6,5%
- known drug or alcohol abuse
- any contraindication to perform exercise training
- acute or chronic infections
- increased bleeding risk by history, INR \> 1,3, use of anticoagulants
Key Trial Info
Start Date :
June 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2019
Estimated Enrollment :
29 Patients enrolled
Trial Details
Trial ID
NCT02196623
Start Date
June 1 2015
End Date
January 1 2019
Last Update
June 29 2025
Active Locations (1)
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1
Hannover Medical School
Hanover, Lower Saxony, Germany, 30625