Status:
UNKNOWN
Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD
Lead Sponsor:
Zhujiang Hospital
Collaborating Sponsors:
Guangzhou Institute of Respiratory Disease
Conditions:
Chronic Obstructive Pulmonary Disease(COPD)
Malnutrition
Eligibility:
All Genders
40-90 years
Phase:
PHASE4
Brief Summary
Insufficient energy intake and systematic inflammation lead to malnutrition in patients with chronic obstructive pulmonary disease (COPD). Nutritional supplementation improves the patients'nutritional...
Detailed Description
Malnutrition is very common in patients with COPD. The main reasons include short intake of energy and systematic inflammation. In our randomized and controlled clinical trial, patients will be divide...
Eligibility Criteria
Inclusion
- Patients from Zhujiang Hospital affiliated from Southern Medical University
- Patients aged between 40 and 90 years old
- Patients gendered into male or female
- Patients with pulmonary function test of FEV1/FVC\<70% and FEV1\<80% predicted
- Patients presenting one or more of the following situations of malnutrition or nutritional risk: BMI \<21 kg/m2 (or\<23 kg/m2 in patients ≥ 65); unintentional weight loss \>10% in the past 6 months; unintentional weight loss \>5% in last month; FFMI \<15 kg/m2 (women) or \<16 kg/m2 (men)
- Patients able to answer question
- Patient able to eat and drink
- Patients who signed informed consent
Exclusion
- Patients with signs of an airway infection
- Patients with malignant disorders
- Patients with recent surgery
- Patients with gastrointestinal ,cardiovascular diseases,neurological diseases or endocrine disease
- Patients with bullae lung
- patients treated with oral steroids or immunosuppressors
- Patients requiring other nutritional supplements or parenteral nutrition
- Patients suffering from acute exacerbation over the previous 4 weeks
- Patients with lack of motivation or poor compliance
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2014
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02197871
Start Date
July 1 2014
End Date
December 1 2014
Last Update
July 23 2014
Active Locations (1)
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1
Zhujiang Hospital,Southern Medical University
Guangzhou, Guangdong, China, 510282