Status:

COMPLETED

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Oral Complications of Radiation Therapy

Stage I Laryngeal Cancer

Eligibility:

All Genders

Phase:

NA

Brief Summary

This pilot trial studies pulsed dye laser in treating patients with post radiation dysphonia. Dysphonia, or vocal cord scarring, can include trouble with the voice when trying to talk, such as hoarsen...

Detailed Description

PRIMARY OBJECTIVES: I. To evaluate the use of pulsed dye laser in treatment of the dysphonia that commonly results after radiation therapy for laryngeal carcinoma. OUTLINE: Patients undergo pulsed ...

Eligibility Criteria

Inclusion

  • Patients suffering from dysphonia after radiation therapy for glottic carcinoma will be included in the study
  • Patients will be included if their initial stage was T1 N0 M0 or T2 N0 M0

Exclusion

  • Patients having previously undergone large surgical resections of the larynx or hypopharynx will be excluded
  • Patients fewer than 1 year out from completion of radiation therapy will be excluded
  • Patients with local disease recurrence would be excluded from the trial
  • Patients in whom the transnasal endoscope is poorly tolerated or patients in whom transnasal endoscopic laryngoscopy is contraindicated will be excluded

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT02198131

Start Date

October 1 2009

End Date

June 1 2016

Last Update

April 26 2023

Active Locations (1)

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Comprehensive Cancer Center of Wake Forest University

Winston-Salem, North Carolina, United States, 27157