Status:
COMPLETED
Clinical Trial of Deferasirox Combination Treatment With Deferiprone In Thalassaemia Patients
Lead Sponsor:
China Medical University Hospital
Conditions:
Beta-thalassemia Major
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Background: Three iron chelators now available on the market differ in toxicity and organ specificity; evidence on standardized chelation protocol remains inconclusive, but patients with transfusion-d...
Eligibility Criteria
Inclusion
- 18 years of age or older
- serum ferritin greater than 2000 ng/mL,
- serum creatinine within normal range for a measuring laboratory
- platelet count exceeding 140000/mm3
- body weight at least 40 Kg
- None had a history of clinical significant of gastrointestinal, hepatic, renal, endocrine, oncologic, infectious, pulmonary or cardiovascular disease
Exclusion
- HIV positive, history of immunologic hypersensitivity to any medication
- women pregnant or breast feeding
- drug or alcohol abuse
- patients showed abnormal or irregular bowel function (defined as more than three bowel movements a day or less than one bowel movement every other day)
- receiving warfarin, digoxin, or anti-arrhythmic or antiseizure medication.
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT02198508
Start Date
July 1 2007
Last Update
July 23 2014
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