Status:
COMPLETED
Apoe Impact Study on Brain Structure and Function, in a Population 45 to 75 Years Old
Lead Sponsor:
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Conditions:
Alzheimer's Disease
Eligibility:
All Genders
45-75 years
Brief Summary
The purpose of this study is to investigate the influence of the APOE genotype on brain morphology, function and metabolism, related to other factors such as cognitive reserve, cognition and episodic ...
Detailed Description
The purpose of this study is to investigate the influence of age and the APOE genotype on brain morphology and function, in 700 cognitively healthy individuals, 45 to 75 years old, recruited from an o...
Eligibility Criteria
Inclusion
- Participant included in the study ClinicalTrials.gov ID: NCT01835717
- APOE genotype obtained before MRI acquisition
- Be willing to perform an MRI and agree to a 2 years longitudinal follow up
- Sign informed consent
Exclusion
- Contraindication to MRI scanning: claustrophobia, pacemaker, history of ocular cerclage, heart valves, aneurysm clips and carrying any metal prosthesis incompatible with MRI.
- Incidental MRI findings that result in the images not being included in the study.
Key Trial Info
Start Date :
April 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2015
Estimated Enrollment :
575 Patients enrolled
Trial Details
Trial ID
NCT02198586
Start Date
April 1 2014
End Date
September 1 2015
Last Update
March 3 2017
Active Locations (1)
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1
Barcelonabeta Brain Research Center
Barcelona, Spain, 08003