Status:

COMPLETED

Comparison Rectal Endoscopic Submucosal Dissection to Endoscopic Mucosal Resection

Lead Sponsor:

Professor Michael Bourke

Conditions:

Colonic Polyps

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

The investigators have recently become proficient in a new, and we believe more effective technique for polyp removal. Known as Endoscopic Submucosal Dissection (ESD). ESD involves removing the polyp ...

Detailed Description

EMR is a very effective procedure for lesions smaller than 20 mm. With this size the polyp can be removed en bloc. En bloc resection is preferred as it minimises the likelihood of residual adenoma and...

Eligibility Criteria

Inclusion

  • Can give informed consent to trial participation
  • Lesion size 20 mm to 50 mm
  • Laterally spreading or sessile polyp morphology

Exclusion

  • Previous resection or attempted resection of target adenoma lesion
  • Endoscopic appearance of invasive malignancy
  • Age less than 18 years
  • Pregnancy
  • Active Inflammatory colonic conditions (e.g. inflammatory bowel disease)
  • Use of anticoagulant or antiplatelet agents other than aspirin less than 5 days prior to procedure
  • American Society of Anesthesiology (ASA) Grade IV-V

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2019

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT02198729

Start Date

July 1 2014

End Date

May 1 2019

Last Update

March 27 2025

Active Locations (1)

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1

Westmead Endoscopy Unit

Westmead, New South Wales, Australia, 2145