Status:

COMPLETED

Effectiveness, Safety & Nurse Management Study of MabThera SC in Patients With Non-Hodgkin's Lymphoma: Real-Life Setting

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Non-Hodgkin's Lymphoma

Eligibility:

All Genders

18+ years

Brief Summary

This prospective, open-label, multicenter, observational study will investigate the effectiveness and safety of MabThera SC (rituximab, subcutaneous) induction therapy in patients with non-Hodgkin's l...

Eligibility Criteria

Inclusion

  • Indication according to the Summary of Product Characteristics (SPC) for MabThera SC formulation:
  • As treatment of previously untreated patients with stage III-IV follicular lymphoma in combination with chemotherapy
  • As treatment of patients with CD20 positive diffuse large B cell non-Hodgkin's lymphoma in combination with chemotherapy
  • At least 4 treatment cycles with MabThera is planned
  • Patients \>/= 18 years at inclusion
  • Patients written informed consent
  • Treatment decision to prescribe MabThera SC has been taken by the physician prior to recruitment into the study

Exclusion

  • Contraindications according to SPC for MabThera SC formulation:
  • Hypersensitivity for the active substance or murine antibodies, hyaluronidase or any other excipients
  • Active and severe infections
  • Patients with severe immunsuppression
  • Patient included in clinical trials with experimental pharmaceuticals
  • Pregnancy

Key Trial Info

Start Date :

August 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2016

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT02199288

Start Date

August 1 2014

End Date

July 1 2016

Last Update

November 2 2016

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Eskilstuna, Sweden, 63188

2

Halmstad, Sweden, 301 85

3

Helsingborg, Sweden, 25187

4

Linköping, Sweden, 581 85