Status:
COMPLETED
POC - Transfusion Algorithm Cardiac Study
Lead Sponsor:
University Health Network, Toronto
Conditions:
Heart Diseases
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This multi-centre study will provide sound, generalizable data on the effectiveness of a POC-based algorithm to determine to what extent this guideline can reduce blood product transfusions. Investiga...
Detailed Description
Despite major advances in cardiac surgery, coagulopathy continues to carry a heavy burden in cases that require the use of cardiopulmonary bypass (CPB), occurring frequently and resulting in excessive...
Eligibility Criteria
Inclusion
- Hospital Inclusion:
- Participating hospitals must not currently be using a POC-based blood conservation algorithm; must have an in-hospital RBC transfusion rate of \> 35% and platelet or plasma transfusion rates of \> 20%; must conduct \> 600 cardiac surgeries employing CPB per year; and must have commitments from departments of Anesthesia, Cardiac Surgery, and Laboratory Medicine to support the study and to abide by the algorithm
- Blood transfusion algorithm instituted as standard-of-care at participating hospitals
- All adult (≥ 18 years) patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) will be included in the analysis.
- Exclusion Criteria: Hospitals not meeting inclusion.
Exclusion
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
7402 Patients enrolled
Trial Details
Trial ID
NCT02200419
Start Date
October 1 2014
End Date
September 1 2016
Last Update
December 5 2016
Active Locations (12)
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1
Dr. Charles McAdams
Calgary, Alberta, Canada, T2N 2T9
2
Blaine Achen
Edmonton, Alberta, Canada
3
Dr. Terry Waters
Vancouver, British Columbia, Canada, V5Z 1M9
4
Dr. Sukhpal Brar
Vancouver, British Columbia, Canada