Status:
COMPLETED
Influences of Phenylephrine, Dopamine and Ephedrine on Stroke Volume Variation and Pulse Pressure Variation
Lead Sponsor:
Chinese PLA General Hospital
Conditions:
Circulation
Drug Dose
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Although induced hypertension decreased SVV and PPV,the influences of stroke volume variation and pulse pressure variation caused by phenylephrine,dopamine and ephedrine were unknown.
Detailed Description
Pulse pressure variation (PPV) and stroke volume variation (SVV) during mechanical ventilation have been shown to be effective parameters to predict preload responsiveness. Although induced hypertensi...
Eligibility Criteria
Inclusion
- Their American Society of Anesthesiologists (ASA) physical status was 1 or 2
- Body mass index (BMI) ranged from 18 to 26
- None of the patients had known diabetes mellitus, hypertension, cardiovascular, pulmonary, endocrinological, neurological diseases, or diseases that influenced intravascular fluid volume or balance
- All patients had a preoperative fast for at least 8 h and routine atropine intramuscular injection
Exclusion
- Persistent arrhythmias
- Intraoperative application of vasoactive drugs except phenylephrine, dopamine and ephedrine
Key Trial Info
Start Date :
March 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT02201121
Start Date
March 1 2014
End Date
June 1 2014
Last Update
July 25 2014
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