Status:
UNKNOWN
Effect of Induction and Maintenance of Anesthesia With Etomidate on Hemodynamics and Oxidative Stress in Diabetic Patients
Lead Sponsor:
Zhujiang Hospital
Conditions:
Hemodynamics
Oxidative Stress
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
To explore the effect of induction and maintenance of anesthesia with etomidate on hemodynamics and oxidative stress in diabetic patients.
Eligibility Criteria
Inclusion
- Aged between 18 and 65 years;
- Diabetic patients preparing for elective surgery;
- Body mass index is between 16 and 30 kg/m2;
- Blood glucose is under 8.3 mmol/kg by oral antidiabetic agents or diet control;
- American Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ;
- Expected operation duration is between 2 and 8 h;
- Signed informed consent form.
Exclusion
- Severe cardiac, cerebral, liver, kidney, lung, endocrine disease or infectious disease;
- Chemotherapy or immunotherapy before the surgery;
- Allergy to trial drug or other contraindication;
- Expected or history of difficult airway;
- Suspected abuse of narcotic analgesia;
- Diseases of neuromuscular system;
- Mentally unstable or has a mental illness;
- Trend of malignant hyperthermia;
- Pregnant or breast-feeding women;
- Attendance of other trial past 30 days.
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2015
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02202239
Start Date
September 1 2014
End Date
August 1 2015
Last Update
July 28 2014
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