Status:

ACTIVE_NOT_RECRUITING

Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus

Lead Sponsor:

Massachusetts General Hospital

Collaborating Sponsors:

National Institutes of Health (NIH)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Eosinophilic Esophagitis

Eligibility:

All Genders

14+ years

Phase:

NA

Brief Summary

The goal of this study is to test the feasibility and the tolerability of a tethered spectrally encoded confocal microscopy (SECM) capsule and to use it to image the esophagus.

Detailed Description

96 participants including healthy volunteers, patients with a suspicion of having Eosinophilic Esophagitis (EoE) and patients with a current or prior clinical diagnosis of EoE will be recruited and as...

Eligibility Criteria

Inclusion

  • Participant must be a healthy volunteer
  • OR participant must have a suspicion of EoE
  • OR participant must have a prior clinical suspicion of EoE
  • Participant must be older than 14 years of age
  • Participant must be able to give informed consent

Exclusion

  • Participants with the inability to swallow pills and capsules.
  • Esophageal fistula and/or esophageal strictures with a stricture diameter that is smaller than the diameter of the capsule.
  • Participants with prior endoscopic ablation or resection treatment of Barrett's Esophagus (BE)

Key Trial Info

Start Date :

October 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2028

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT02202590

Start Date

October 1 2013

End Date

December 1 2028

Last Update

October 22 2025

Active Locations (1)

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Massachusetts General hospital

Boston, Massachusetts, United States, 02114