Status:

COMPLETED

Evaluation of Richmond Agitation Sedation Scale According to Alveolar Concentration of Sevoflurane During a Sedation With Sevoflurane in ICU Patients

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Requiring Sedation by Sevoflurane in ICU

Adult Patients

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Describe the Richmond Agitation Sedation Scale (RASS) values corresponding to the values of Minimum alveolar concentration of sevoflurane during sedation of patients in ICU

Detailed Description

Prospective clinical study in ICU with sedated ventilated patients with sevoflurane using the Mirus® system. Pharmacological study of the concentration-effect relationship by administration at increas...

Eligibility Criteria

Inclusion

  • Requiring sedation by sevoflurane in ICU
  • Adult patients
  • Patients covered by french health care system
  • Patients who have given their consent or his family

Exclusion

  • Pregnant or lactating women
  • Sevoflurane anaphylaxia
  • Known or suspected risk of malignant hyperthermia
  • Refusal Protocol
  • Brain-damaged patients
  • Hemodynamic conditions not compatible with the use of sevoflurane
  • ARDS patients
  • Minor patients

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2014

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT02202720

Start Date

August 1 2014

End Date

November 1 2014

Last Update

November 26 2014

Active Locations (1)

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CHU Clermont-Ferrand

Clermont-Ferrand, France, 63003