Status:
COMPLETED
Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
National Evidence-based healthcare Collaborating Agency (NECA)
Asan Medical Center
Conditions:
Sepsis
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
This clinical trial is aimed to show a procalcitonin-guided treatment algorithm may shorten duration of antibiotic therapy safely and cost-effectively in sepsis patients of Korean ICU.
Eligibility Criteria
Inclusion
- All patients with suspicious or confirmed sepsis at admission or during stay in ICU
- Patients with antibiotic duration of less than 48 hours before enrollment
Exclusion
- Age less than or equal to 18 years
- Known pregnancy
- Specific infections for which long-term antibiotic treatment for 3 weeks more is strongly recommended: infective endocarditis, empyema, osteomyelitis et al.
- severe immunocompromised patients : HIV infected patients (CD4 count \< 200 cells/mm3), Neutropenia (ANC count \< 500/mm3)
- Presence of do-not-resuscitate order
Key Trial Info
Start Date :
August 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT02202941
Start Date
August 1 2014
End Date
March 1 2015
Last Update
November 2 2018
Active Locations (4)
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1
Seoul National University Hospital
Seoul, South Korea, 110-744
2
Samsung Medical Center
Seoul, South Korea, 135-710
3
Asan Medical Center
Seoul, South Korea
4
Severance Hospital
Seoul, South Korea