Status:
COMPLETED
Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure
Lead Sponsor:
Texas Tech University Health Sciences Center
Conditions:
Sepsis
Respiratory Failure
Eligibility:
All Genders
18-89 years
Phase:
PHASE4
Brief Summary
Patients with infections in their blood often become very sick. These patients are usually put in an intensive care unit for careful observation and treatment. These patients may develop a low blood p...
Detailed Description
Patients admitted to the MICU with acute respiratory care and possible sepsis will be evaluated and managed by the internal medicine MICU team. This team includes faculty members, pulmonary fellows, a...
Eligibility Criteria
Inclusion
- Men and women 18-89 years old
- with the diagnosis of sepsis (as specified below) within the previous 24 hours
- who require mechanical ventilation, and
- provide informed consent either personally or by an authorized representative.
Exclusion
- Patients with documented allergies to propofol, dexmedetomidine, fentanyl, eggs or egg products, or soy or soy products.
- A heart rate less than 50 beats/minute or grade 2 or 3 AV heart block
- Mean arterial pressure less than 55 mmHg despite appropriate fluid resuscitation and vasopressor support.
- Current triglyceride level \> 400 mg/dl
Key Trial Info
Start Date :
August 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 22 2016
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT02203019
Start Date
August 1 2014
End Date
September 22 2016
Last Update
March 2 2020
Active Locations (1)
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1
University Medical Center
Lubbock, Texas, United States, 79415