Status:
COMPLETED
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
Lead Sponsor:
University of Debrecen
Conditions:
Propofol-anaesthesia Via Target-controlled Infusion
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
Purpose: The purpose of this study is to examine the effect of different carbon-dioxide concentrations on cerebral CO2 sensitivity and the resistance and stiffness of systemic arteries during anesthe...
Detailed Description
Study protocol: \- The study is conducted in four stages: in the first stage, measurements are performed preoperatively in awake patients. Patients are placed in supine position and mean arterial blo...
Eligibility Criteria
Inclusion
- Above the age 18
- American Society of Anesthesiologists (ASA) physical classification I. or II.
- Patients undergoing elective varicotomy, inguinal hernioplasty or breast surgery in general anesthesia
Exclusion
- Patients with cerebral, cardiac or systemic vascular disorders (hypertension, diabetes)
- Patients receiving medication that affects the blood vessels (antihypertensive, antidiabetic, antiarrhythmic medications)
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT02203097
Start Date
January 1 2014
End Date
December 1 2016
Last Update
March 9 2017
Active Locations (1)
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1
University of Debrecen Medical and Health Science Center Department of Anesthesiology and Intensive Care
Debrecen, Hungary, 4032