Status:

COMPLETED

Glycemic and Insulinemic Response With Different Sources of Soluble Fiber in Patients Type 2 Diabetes Mellitus

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Collaborating Sponsors:

Federal University of Rio Grande do Sul

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Conditions:

Dietary Modification

Diabetes Mellitus Type 2

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

To compare the acute effect of soluble fiber intake from foods or supplement after a common meal on postprandial plasma glucose and insulin in patients with type 2 diabetes. The hypothesis is a meal w...

Detailed Description

Three breakfasts (high amount of fiber from diet food sources - HFD, high amount of soluble fiber from guar gum supplement - HFS and usual amount of fiber -UF), isocaloric and similar distribution of ...

Eligibility Criteria

Inclusion

  • Patients with type 2 diabetes
  • Body Mass Index (BMI) \<= 35 kg / m²
  • Hemoglobin A1c (HbA1c) \<= 9%

Exclusion

  • Serum creatinine \>2.0 mg/dL
  • Digestive diseases (e.g. malabsorption)
  • Severe autonomic neuropathy (presence of symptomatic postural hypotension, gastroparesis, diabetic diarrhea)
  • Recent cardiovascular event
  • Cachexia
  • Psychiatric disorder with impairment of understanding
  • Participating in other research protocol

Key Trial Info

Start Date :

August 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2017

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT02204384

Start Date

August 1 2014

End Date

January 1 2017

Last Update

February 14 2017

Active Locations (1)

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Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90035-903