Status:

COMPLETED

Brain-Behavior Interactions in Tic Suppression

Lead Sponsor:

University of Minnesota

Conditions:

Tourette's Syndrome

Chronic Motor Tic Disorder

Eligibility:

All Genders

12-18 years

Brief Summary

The purpose of this study is to examine how the brain and environment interact to influence children's ability to suppress tics using a medical technology called Transcranial Magnetic Stimulation (TMS...

Detailed Description

Objectives: This study will recruit youth with chronic tics. Chronic tics are the most common movement disorder in children. The goal of the study is to learn how the brain and environment influence c...

Eligibility Criteria

Inclusion

  • Presence of motor and/or vocal tics for at least one year
  • English fluency

Exclusion

  • Participants with medical conditions that are contraindicated for TMS (history of any known intracranial pathology, epilepsy or seizures, traumatic brain injury, brain tumor, stroke, implanted medical devices, current pregnancy or girls of childbearing age not using effective contraception, or any other serious medical conditions
  • Left-handedness
  • Previous diagnosis of psychosis, autism spectrum disorder, mental retardation, or cognitive disability
  • Inability to undergo MRI
  • Substance abuse or dependence within the past year
  • History of ≥3 sessions of Habit Reversal Therapy or other treatment primarily comprised of tic suppression strategies
  • Current suicidal intent
  • Current neuroleptic medications, as these medications are known to lower seizure threshold

Key Trial Info

Start Date :

July 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2019

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT02205918

Start Date

July 1 2017

End Date

September 1 2019

Last Update

July 17 2020

Active Locations (1)

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1

University of Minnesota

Minneapolis, Minnesota, United States, 55455