Status:
COMPLETED
Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Malaria
Eligibility:
All Genders
18-35 years
Brief Summary
Background: \- Malaria is a disease that affects many people in Mali and in Africa. It is caused by germs that are spread by mosquito bites. Researchers are creating vaccines that they hope will prev...
Detailed Description
A vaccine which interrupts malaria transmission (VIMT) is a critical tool to achieve the ultimate goal of eradication of this disease. VIMTs work by inducing humoral responses in vaccinated individual...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Currently enrolled in the PfSPZ Vaccine trial.
- Willingness to participate in the study as evidenced by signing the informed consent document, or by fingerprinting the consent document and obtaining the signature of a witness.
- EXCLUSION CRITERIA:
- Refusal to participate
- Known history of abnormal reaction to mosquito bites
- Any condition that in the opinion of the investigator would jeopardize the safety or rights of a volunteer participating in the DSF or EH procedures or would render the volunteer unable to comply with the Feeding Assay Protocol.
- Pregnancy
- Any condition that in the opinion of the investigator would withdraw the volunteer from vaccine trial.
Exclusion
Key Trial Info
Start Date :
July 16 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 16 2014
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT02206451
Start Date
July 16 2014
End Date
July 16 2014
Last Update
December 17 2019
Active Locations (1)
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1
Malaria Research and Training Center
Bamako, Mali