Status:

COMPLETED

Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

Lead Sponsor:

Texas Cardiac Arrhythmia Research Foundation

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

50-75 years

Brief Summary

The purpose of this study is to assess if pre-ablation levels of inflammatory biomarkers serve as independent predictors of procedure outcome To evaluate the inflammatory activation following catheter...

Detailed Description

Specific Aim: The purpose of this prospective study is to evaluate the role of inflammatory biomarkers in predicting procedure-outcome in AF patients undergoing catheter ablation. Background: AF is t...

Eligibility Criteria

Inclusion

  • Age: 50-70 years
  • Patients undergoing catheter ablation of atrial fibrillation
  • Able and willing to give written consent

Exclusion

  • Reversible causes of AF such as pericarditis and hyperthyroidism
  • Associated chronic inflammatory diseases such as chronic gingivitis or peri-odontitis, rheumatoid Arthritis, IBD including Ulcerative Colitis and Crohn's disease, Lupus, Ankylosing Spondylitis, COPD, psoriasis, vasculitis
  • Any other co-morbid conditions except Diabetes and hypertension
  • Patients taking long-term anti-inflammatory, steroid medication, or immune suppression medication.

Key Trial Info

Start Date :

July 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2016

Estimated Enrollment :

155 Patients enrolled

Trial Details

Trial ID

NCT02208102

Start Date

July 1 2014

End Date

May 1 2016

Last Update

October 19 2017

Active Locations (1)

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Texas Cardiac Arrhythmia Institute, St. david's Medical Center

Austin, Texas, United States, 78727