Status:

UNKNOWN

Alzheimer's Disease, Art and Garden

Lead Sponsor:

Central Hospital, Nancy, France

Conditions:

Alzheimer Disease

Eligibility:

All Genders

60+ years

Phase:

NA

Brief Summary

Gardens and art represent public spaces and support venues of interactions and emotions, seeking not only a variety of conversational themes but also various cognitive skills such as mnemonic skills. ...

Detailed Description

RESEARCH METHODOLOGY / EXPERIMENTAL DESIGN Open, monocentric, controlled (group of healthy control subjects) study. Population: 2 groups: Group A "Alzheimer group": patients with mild to severe sta...

Eligibility Criteria

Inclusion

  • aged 60 to 100 years
  • able to walk independently, that is to say without recourse to aid, whether human or technical, except for a simple cane
  • have never been in the garden " art, memory and life " of the Paul Spillmann Centre
  • gave their written consent after receiving clear and intelligible written and oral information
  • with a diagnosis of a probable mild to severe stage of Alzheimer's disease according to NINCDS-ADRDA diagnostic criteria (McKhann et al., 1984) within the last 2 months prior to inclusion
  • score less than or equal to 4 on the Hachinski Ischemic Scale (Hachinski et al., 1984) within the last 2 months prior to inclusion
  • Folstein MMSE score between 7 and 24 inclusively within the last 2 months prior to inclusion
  • score of 4, 5 or 6 on the Reisberg Global Deterioration Scale (Reisberg et al., 1982) within a 2-month delay prior to inclusion
  • specific drug treatment for Alzheimer's disease, unchanged since at least 2 months (cholinesterase inhibitor and memantine)
  • no change in psychotropic treatment within 48 hours prior to inclusion

Exclusion

  • lack of insurance coverage
  • sensory deficit interfering with the designated tasks in the study
  • phasic disorders interfering with the designated tasks in the study
  • history of head trauma (with loss of consciousness)
  • chronic alcoholism
  • refusal or inability to obtain the informed written consent of the subject
  • persons subject to a legal protection order
  • severe depression: score \> 20 on the GDS (Geriatric Depression Scale) scale at inclusion
  • other neurological or psychiatric disorders potentially affecting the assessment
  • current or planned participation to other research involving neuropsychological evaluations and/or drug trial, up until the end of the current study

Key Trial Info

Start Date :

July 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2017

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02208193

Start Date

July 1 2014

End Date

September 1 2017

Last Update

July 30 2015

Active Locations (1)

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1

CHU Nancy

Nancy, France, 54000