Status:

COMPLETED

Impact of Automatic Positive Airway Pressure on Treatment Compliance in OSA Patients Awaiting Bariatric Surgery

Lead Sponsor:

Laval University

Collaborating Sponsors:

GROUPE DE RECHERCHE EN SANTÉ RESPIRATOIRE DE L'UNIVERSITÉ LAVAL (GESER)

Conditions:

Obstructive Sleep Apnea

Treatment Compliance

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent dynamic obstruction of the upper airways that causes a fall in oxygen saturation, reflex sympathetic activation and sleep micr...

Eligibility Criteria

Inclusion

  • Obese patients with a BMI ≥ 40 kg/m2 or ≥ 35 kg/m2 with additional risk factors for cardiovascular disease and eligible for bariatric surgery;
  • Laparoscopic bariatric surgery planned in 2-6 months. Procedures include biliopancreatic diversion with duodenal switch and sleeve gastrectomy;
  • Recent diagnosis of obstructive sleep apnea made by a sleep study. The sleep study must be a overnight pulse oximetry showing a 3% desaturation index ≥ 25/hour or a polysomnography with a apnea + hypopnea index (AHI) ≥ 25/hour\* ;
  • No previous use of positive airway pressure device;
  • ≥18 year old.

Exclusion

  • Severe comorbidities (respiratory, cardiac, neurologic or metabolic unstable disease);
  • Central sleep apnea;
  • Obesity hypoventilation syndrome;
  • Planned bariatric surgery by laparotomy;
  • Contraindications to positive airway pressure therapy: pneumothorax within the preceding 6 months, cerebrospinal fluid leak, cranial surgery or trauma within the last year.

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 16 2018

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT02209220

Start Date

September 1 2014

End Date

March 16 2018

Last Update

August 5 2019

Active Locations (1)

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1

Institut universitaire de cardiologie et de pneumologie de Québec

Québec, Quebec, Canada, G1V 4G5