Status:
COMPLETED
Beta-carotene Absorption and Bioconversion to Vitamin A From Biofortified Cassava Gari
Lead Sponsor:
USDA, Western Human Nutrition Research Center
Collaborating Sponsors:
HarvestPlus
Conditions:
Vitamin A Deficiency
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
The goal of the research study is to determine the absorption, metabolism, and bioconversion of carotenoids such as beta-carotene to vitamin A from gari made with biofortified cassava compared to a mi...
Detailed Description
Vitamin A deficiency (VAD) is a major public health problem in most of the developing world, especially Southern Asia and Sub-Saharan Africa. The primary issue in vitamin A deficient populations is th...
Eligibility Criteria
Inclusion
- healthy
- non-pregnant, non-lactating
- premenopausal women
- non-smoking
- body mass index between 18 and 35
- total cholesterol concentrations between 90 and 225 mg/dL
- blood pressure under 140/90 mm Hg
Exclusion
- anemia, Hemoglobin less than 11.5 g/dL
- medications such as gemfibrozil, niacin, lovastatin, simvastatin, ezetimibe)
- medications that affect retinoid or carotenoid metabolism (Accutane)
- medications that impair fat absorption (Xenical, orlistat)
- dietary supplements containing vitamin A
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT02210507
Start Date
July 1 2014
End Date
December 1 2014
Last Update
January 12 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
USDA, ARS, Western Human Nutrition Research Center
Davis, California, United States, 95616